Translational Clinical Studies Research Committee 2021

Projects approved for funding in 2021

CodeTitleOrganisationLead PIFunding AmountAbstractFinal Summary
TCS/21/02Development of a novel anti-cancer Natural Killer cell-based immunotherapyUniversity of GlasgowProfessor Gerard Graham£299,999TCS/21/02 AbstractTCS/21/02 Final Summary
TCS/21/03Early detection of Alzheimer’s disease with glucoCEST MRI: a proof of concept studyUniversity of AberdeenDr Gordon Waiter£260,978TCS/21/03 AbstractTCS/21/03 Final Summary
TCS/21/04A single-centre, randomised, open label, blinded end-point, safety and efficacy trial of conventional versus higher dose acetylcysteine in patients with paracetamol overdose. (The High SNAP Trial).University of EdinburghProfessor James Dear£295,509TCS/21/04 AbstractProject Active
TCS/21/05Developing representative models of the blood-tumour barrier to enhance drug development for glioblastoma.University of GlasgowProfessor Anthony Chalmers£296,864TCS/21/05 AbstractProject Active
TCS/21/09Proof-of-concept for using a novel formulation of metformin (Metformin Delayed Release) to optimise treatment of gestational diabetesUniversity of EdinburghProfessor Rebecca Reynolds£299,259TCS/21/09 AbstractTCS/21/09 Final Summary
TCS/21/11PRevention and Early detection of Breast cancer in high-RISK premenopausal population through mammary lipid composition using novel imagingUniversity of AberdeenDr Jiabao He£296,114TCS/21/11 AbstractTCS/21/11 Final Summary
TCS/21/25Dissecting the transcriptomic and phenotypic reprogramming of myeloid cells that mediate chemoresistance in cholangiocarcinomaUniversity of GlasgowDr Chiara Braconi£299,997TCS/21/25 AbstractTCS/21/25 Final Summary
TCS/21/30A window in the brain 2:  Novel quantitative seizure detection tool for paediatric critical care.  A multi-centre feasibility studyUniversity of EdinburghDr Tsz-Yan Milly Lo£298,740TCS/21/30 AbstractTCS/21/30 Final Summary
TCS/21/31Targeting investigation and treatment in patients with type 2 myocardial infarction (TARGET – Type 2): A pilot randomised controlled trialUniversity of EdinburghDr Andrew Chapman£258,738TCS/21/31 AbstractTCS/21/31 Final Summary
TCS/21/39PET/MRI (Positron Emission Tomography/Magnetic Resonance Imaging) to Improve Staging and Personalise Treatment for Prostate Cancer: PRISTINE StudyUniversity of EdinburghDr Rishi Ramesh / Dr David Noble£276,554TCS/21/39 AbstractProject Active
TCS/21/43First in Human Clinical Trial of SARS-CoV-2 Allogeneic Virus Specific T cellsScottish National Blood Transfusion ServiceProfessor Marc Turner£280,403TCS/21/43 AbstractTCS/21/24 Final Summary